1. Duty origin
In this design, we take dodecanol and Ethylene oxide as the main material. The determination of  the optimum choice and optimization of  the production process, material balance and energy balance of the ethylene oxide, esterification, sulfonation, the selection and design the main equipment oxidation reactor, the esterification of vertical reactor, sulfonation reactor had all be made. In  addition, the preliminary site selection and facility layout design, environmental analysis and workshop production cost estimates had been done.
2. Design standard
This design has referred to below the national standard and the stipulation.
(1)  Production  process dangerous material and harmful factor classification and code.
（GB/T13816-1992）
(2) Commonly used dangerous chemistry classified standard.（GB13690-1992）
(3)  Inpressure vessel chemistry medium model harm and explosion hazard degree
classification (HGJ43-1991)
(4) Factory fire protection stipulation (GBJ16-1987)   
(5) The sewage synthesis discharges the stipulation (GBJ8978)
(6) The steel pins down the pressure vessel (GB150)
(7) Shell type heat interchanger standard (GB151)
(8) Craft system arrangement of equipment design stipulation (HG20570)
(9) Chemical installment piping arrangement design stipulation (HG/T20549)
3. Principle of design and main design standard
Safe:In the chemical production the massive matter are flammable, explosiveor are virulent. Therefore, the design must fully consider each kind is obvious and the latent danger, the guarantee production personnel'shealth and the security. Ease of operation: While determines each production process and equipment, but also must reasonably determine the operating condition. Because of it to the production process and the equipment establishment and it’s the function display and the control plan determination, all has the direct relations. Investment province: Namely the request economically uses the equipment investment, the construction invests, the public project investment and the manpower cost. Is advantageous for the installment: The factory arrangement should satisfy the construction and the installment work request. Specially  should consider the large-scale equipment the hoisting, in the factory the path pavement structure and the load standard and so on should satisfy the work the request.
KeyWords：Sodium dodecanol polyoxyethylene ether succinate sulfonate; Surfactant; Process design
目   录
1  绪论   1
1.1  产品性质   1
1.2  市场情况及其前景   1
2  文献综述  3
2.1  脂肪醇聚氧乙烯醚的合成  3
2.1.1  环氧乙烷加成法  3
2.1.2  Williamson 合成法  4
2.2  磺酸基的连接方法   4
2.2.1  硫酸酯盐转化法  5
2.2.2  Streck 转化法   5
2.2.3  羟乙基磺酸钠法  5
2.2.4  溴（氯）乙磺酸钠法  5
2.2.5  烯烃加成反应制备法  6
2.2.6  丙烷磺内酯法   6
2.3  合成路线比较及选择  7
2.3.1  脂肪醇聚氧乙烯的合成   7
2.3.2  磺酸基的连接方法  7
3  设计方案  8
3.1  合成原料  8
3.2  反应条件及原理    8
3.3  反应流程  9
4  工艺计算    10
4.1  物料衡算   10
4.1.1  物料衡算依据   10
4.1.2  磺化反应物料衡算    10
4.1.3  酯化反应物料衡算    12
4.1.4  乙氧基化反应物料衡算   14
4.2  设备计算及选型  15 每年600吨十二醇聚氧乙烯醚琥珀酸单酯磺酸钠生产车间的工艺设计(2):http://www.751com.cn/huaxue/lunwen_22467.html