摘要：本研究论文主要以纤文素为壁材，以紫外线吸收剂二苯甲酮-3为芯材，制备成水包油型的微粒粒子，并对影响乳液粒子粒径大小、包埋率等因素进行了考察，在此基础上，将制备的包覆了紫外线吸收剂的乳液粒子加入防晒霜中，并对制备的防晒霜进行稳定性评价。结果表明：得到的包覆二苯甲酮-3的水包油型乳液粒子为核-壳结构呈球形；通过纳米激光粒度分析仪测得平均粒径在100~300nm；通过紫外可见分光光度计测得二苯甲酮-3包埋率在7％~15％之间，利用该粒子制备得到的防晒霜具有良好的稳定性能，该粒子具有潜在的应用前景。7310
关键词：二苯甲酮-3；纤文素；纳米乳液粒子；粒径；包埋率；防晒霜；
Sunscreens containing UV absorber coating Preparation and efficacy evaluation
Abstract：This study mainly cellulose as wall material to UV absorber benzophenone-3 as the core material, oil in water were prepared particles particles, and particle size emulsion particles impact, embedding rate and other factors were investigation, on this basis, the prepared emulsion coated with a UV absorber particles added to sunscreen, sunscreen and prepared for stability evaluation. The results showed that: the resulting coated benzophenone-3 oil in water type emulsion particles as core - shell structure spherical; through nanometer laser particle size analyzer measured an average particle size of 100 ~ 300nm; through UV-visible spectrophotometry meter measured benzophenone-3 embedding rate of 7% to 15%, and use of the particles prepared by the sunscreen has a good stability of the particles have potential applications.
Keyword：Benzophenone-3; cellulose; nanometer emulsion particles; diameter; embedding rate; sunscreen;
目录
1 绪论 1
1.1国内外对防晒产品的研究现状 1
1.2防晒剂的基本概况 2
1.2.1紫外线对人体的影响 2
1.2.2防晒剂的作用机理 2
1.2.3紫外防晒剂的种类 3
1.3纳米乳液粒子包埋技术概述及研究现状 4
1.4化妆品中纳米乳液粒子包埋制备技术的介绍 6
1.5本课题研究的目的与意义 6
2 实验内容 8
2.1实验原料与设备 8
2.1.1实验原料 8
2.1.2实验所用设备 8
2.2实验方法 9
2.2.1样品的制备的初期工艺探索 9
2.2.2含二苯甲酮-3纳米乳液粒子的制备 9
2.2.3 空白O/W型防晒霜的制备 10
2.2.4 包埋二苯甲酮-3微粒防晒霜的制备 10
2.2.5 防晒霜配方如下 11
2.3实验制备流程图 12
2.4包覆二苯甲酮-3纳米乳液粒子的表征测试 12
2.4.1 纳米乳液粒子的形貌表征 12
2.4.2 纳米乳液粒子粒径尺寸 12
2.4.3 纳米乳液粒子包埋率表征标准曲线的制作 13
2.4.4 包覆二苯甲酮-3纳米乳液粒子的包埋率的测定 13
2.4.5 防晒霜的感官和耐热耐寒等功效评价 13
3 实验结果与讨论 15
3.1纳米乳液粒子粒径的影响因素 15
3.1.1 壁材与芯材的配比对粒径大小的影响 15
3.1.2 乳化剂用量的影响 16
3.1.3 稳定剂（PVA)用量的影响 16
3.2包覆二苯甲酮-3纳米乳液粒子的电镜表征 17
3.2.1电镜表征 17
3.3包覆二苯甲酮-3纳米乳液粒子的包埋率的影响因素 17 含包覆紫外线吸收剂粒子防晒霜的制备及其功效评价:http://www.751com.cn/huaxue/lunwen_5210.html