摘要基因芯片技术发展始于20世纪90年代,是一种能够对大量遗传信息进行快
速、高通量、并行检测的多学科交叉技术,在生物检测、医学检验和药物筛选等
众多领域得到了广泛应用。制备基因芯片的主要设备是基因芯片点样仪。本文根
据基因芯片点样技术的要求,结合微流体脉冲驱动-控制技术设计一种应用于基
因芯片点样的三文精密工作台。三文精密工作台硬件部分包括工作台、步进电机
控制电路和PC机, 软件部分包括三文精密工作台步进电机驱动程序和上位机人机
界面软件。三文精密工作台的设计结合了PC机适用于大规模程序计算和单片机
适用于现场控制的优点,采用PC机与单片机联机运行的工作方式,两者通过
RS-232串行通信进行数据传输。PC机用于系统的数据处理和点样图像仿真;单
片机用于响应PC机的各种控制命令,对步进电机驱动器发出命令,驱动步进电机
运行,实现三文精密工作台用于基因芯片点样的功能。5646
关键词:基因芯片点样仪 三文精密工作台 单片机 步进电机 串口通信
毕业设计说明书(论文)外文摘要
Title The machanical structure and control system design of
a three-dimensional precision stage
Abstract
Gene chip technology through which a large number of genetic information
can be detected fast, high-throughput and parallel is a kind of
multi-disciplinary technology. The development of Gene chip technology
began in 1990s. Since then, this technology has been widely applied in
many areas of biological testing, medical examination and drug screening.
The main device for gene chip preparation is the gene chip microarray.
To meet the requirements of gene chip microarray technology, a three-
dimensional precision stage combined with the micro-fluid pulse
drive-control system has been designed. The 3-D(three-dimensional)
precision stage is instructed with hardware part and software part. The
hardware includes a 3-D stage, stepper motor control circuits and a
PC(computer), and the software includes a 3-D precision stage stepper
motor driver program and a human-computer interaction interface. The
design of a 3-D precision stage has the advantages that PC is suitable
for large-scale calculating program and SCM (Single Chip Microcomputer)
for the field control. The PC and the SCM cooperate online, and all the
data transmission is via RS-232 serial communication. PC is used for data
processing and microarray image simulation and SCM is used to respond to
the PC control commands, give an order to drive a stepper motor running
to achieve the movement of the gene chip microarray.
Keywords: gene chip microarray three-dimensional precision stage SCM
stepper motor driver serial communication
目 次
1. 绪论...1
1.1. 基因芯片点样技术...1
1.1.1. 基因芯片1
1.1.2. 基因芯片点样技术..1
1.2. 基因芯片点样仪.2
1.2.1. 基因芯片点样仪结构型式..2
1.2.2. 三文精密工作台点样仪5
1.3. 研究内容.6
2. 三文精密工作台总体方案设计..7
2.1. 设计方案.7
2.2. 设计指标.7
2.3. 硬件组成.8
2.3.1. 上位机....8
2.3.2. 下位机核心板....9
2.3.3. 步进电机驱动器9
2.4. 工作坐标系的确定...9
2.5. 本章小结.....10
3. 三文精密工作台机械结构设计11
3.1. 机械结构总体设计.11
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