纯钛表面纳米化及其生物活性的研究

摘要在所有生物医用金属材料中,钛及其合金的综合力学性能优良,并且具有良好生物性能，被广泛应用于外科植入材料，如人工骨，人工关节等植入体。可是钛强度较低，耐磨性差，弹性模量与骨的弹性模量相差还较大，使医疗过程中发生了应力遮挡效应使骨折不能正常愈合恢复。为了降低纯钛的弹性模量避免应力遮挡效应，同时提高耐磨耐蚀行，改善纯钛的生物性能，本文采用了高能喷丸(HESP)法对工业纯钛进行表面纳米化。利用扫描电子显微镜对表层组织观察，能谱仪进行物相分析，测量表层的显微硬度，测量润湿角。继续对表面纳米化钛进行后处理包括过氧化氢处理，碱处理等，最后在模拟体液培养4周。研究结果表明：利用表面纳米化技术可以在纯钛表面制备出一定厚度的纳米结构表层，获得一个具有梯度结构的钛材料。通过这纳米层的优异性可提高钛的表面耐磨性，降低了钛的弹性模量。随着喷丸时间延长，塑性变形层的厚度增加。表面纳米化钛经过酸，碱处理后，在模拟体液中培养4周发现表面上类骨成分羟基磷灰石沉积出来。而在没有经过表面纳米化钛表面上的HA含量很少。显然，表面纳米化有效提高了羟基磷灰石的沉积速度，密度和涂层与基体结合力，从而改善了钛材料表层生物活性，相容性。68243

毕业论文关键词：表面纳米化；高能喷丸；应力遮挡；酸处理；碱处理；羟基磷灰石。

毕业设计说明书(论文)外文摘要

Title The study of pure Titanium Surface Nanocrystallization and its bioactivity

Abstract

In the biomedical metallic materials, The comprehensive performance of pure titanium and its alloys is most excellent, widely used in surgical implant materials, as artificial bone, artificial joints,etc. implants. But low strength, poor wear resistance, high elastic modulus results in the stress shielding effect, have an adverse impact on healing of fracture .in order to reduce the elastic modulus of pure titanium so as to decrease stress shielding. Improve the wear resistance and the bioactivity of pure titanium. The surface nanocrystallization is approached on a pure titanium by using High Energy Shot Peening (HESP) technique, observe the surface tissue by Scanning Electron Microscope(SEM), phase analysis by Energy Dispersive Spectrometer(EDS)，measure microhardness of Nanostructure surface layer，measure of wetting angle. And then pots-processing (Acid, alkali treatment) on the surface nanocrystallization of titanium. The results showed that: preparation a certain thickness of the nano structure surface on the surface of pure titanium by Surface Nanocrystallization.Obtain a gradient structure of titanium.Improve wear resistance of titanium by the excellent performance of the nano-layer,reducing a modulus of elasticity of titanium reduce stress shielding. Acid treatment,alkali treatment after,cultivate in the simulated body fluid for 4 weeks, generated Hydroxyapatite(HA). Surface Nanocrystallization improve deposition rate, density of HA, thus improve bioactivity, compatibility of surface of Titanium.

Keywords Surface Nanocrystallization;High energy shot peening;Stress shielding; Acid treatment; Alkali treatment; Hydroxy apatite.

Keywords Micro-arc oxidation Alkali treatment Pre-calcification treatment bioactivity

1 引言 1

1.1 概述 1

1.2 医用钛的性能 1

1.2.1 力学性能 1

1.2.2 生物性 1 纯钛表面纳米化及其生物活性的研究:http://www.751com.cn/cailiao/lunwen_76716.html